Quick Answer
Diarrhea affects 15-20% of semaglutide users, typically appearing in weeks 2-4 of treatment. It's usually mild and self-limiting.
Common (15-20% of users)
Why This Happens
Semaglutide increases gastric motility in some people after the initial slowdown. The medication also affects bile acid metabolism, which can increase stool frequency.
If side effects are limiting your progress, a provider can adjust dosing or switch medications based on your response. The right medication match can make all the difference.
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Check Availability →Is It Serious?
Usually mild. Staying hydrated and avoiding high-fat foods helps significantly.
When to Contact Your Doctor
- If diarrhea is severe or persistent beyond 2 weeks, tell your doctor.
- Monitor for dehydration, especially if combined with other side effects.